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INDICATION & USAGE

IXIARO is a vaccine indicated for the prevention of disease caused by JE virus, approved for use in individuals 2 months of age and older.

Important Safety Information

Severe allergic reaction (e.g., anaphylaxis) after a previous dose of IXIARO, any other Japanese encephalitis vaccine, or any component of IXIARO, including protamine sulfate ─ a compound known to cause hypersensitivity reactions in some individuals ─ is a contraindication to administration of IXIARO.  Individuals with a history of severe allergic reaction to another Japanese encephalitis vaccine may be referred to an allergist for evaluation if immunization with IXIARO might be considered.

Vaccination with IXIARO may not protect all individuals.  Immunocompromised individuals may have a diminished immune response to IXIARO. Syncope can occur in association with administration of injectable vaccines, including IXIARO. Procedures should be in place to prevent injury from falling and manage syncopal reactions.

The most common (>10%) adverse reactions were: fever, irritability, diarrhea, and injection site redness in infants 2 months to <1 year of age; fever in children 1 to <12 years of age; pain and tenderness in adolescents 12 to <18 years of age; and, headache, myalgia, and injection site pain and tenderness in adults.

Healthcare practitioners are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit www.vaers.hhs.gov or call 1-800-822-7967.  Healthcare practitioners are also encouraged to report inadvertent use in pregnant women to Valneva at 844-349-4276 (8443-IXIARO).

Please see full Prescribing Information.

    

INDICATION & USAGE

IXIARO is a vaccine indicated for the prevention of disease caused by JE virus, approved for use in individuals 2 months of age and older.

Important Safety Information

Severe allergic reaction (e.g., anaphylaxis) after a previous dose of IXIARO, any other Japanese encephalitis vaccine, or any component of IXIARO, including protamine sulfate ─ a compound known to cause hypersensitivity reactions in some individuals ─ is a contraindication to administration of IXIARO.  Individuals with a history of severe allergic reaction to another Japanese encephalitis vaccine may be referred to an allergist for evaluation if immunization with IXIARO might be considered.

Vaccination with IXIARO may not protect all individuals.  Immunocompromised individuals may have a diminished immune response to IXIARO. Syncope can occur in association with administration of injectable vaccines, including IXIARO. Procedures should be in place to prevent injury from falling and manage syncopal reactions.

The most common (>10%) adverse reactions were: fever, irritability, diarrhea, and injection site redness in infants 2 months to <1 year of age; fever in children 1 to <12 years of age; pain and tenderness in adolescents 12 to <18 years of age; and, headache, myalgia, and injection site pain and tenderness in adults.

Healthcare practitioners are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit www.vaers.hhs.gov or call 1-800-822-7967.  Healthcare practitioners are also encouraged to report inadvertent use in pregnant women to Valneva at 844-349-4276 (8443-IXIARO).

Please see full Prescribing Information.

    

 

 

Japanese Encephalitis (JE)

One vaccine can help protect them4

IXIARO® (Japanese Encephalitis Vaccine, Inactivated Adsorbed) is the only JE vaccine available in the United States.4

IXIARO® (Japanese Encephalitis Vaccine, Inactivated Adsorbed) is the only JE vaccine available in the United States.4

What is IXIARO®?

IXIARO® is a vaccine indicated for the prevention of disease caused by Japanese encephalitis virus for people 2 months of age and older.16

Immune Response Kinetics After Primary Immunization16

IXIARO® has an established safety and tolerability profile16

  • The safety of IXIARO® has been confirmed in multiple clinical studies16
  • IXIARO® has been used across Europe and the USA since 20094
  • Common adverse reactions include fever, irritability, diarrhea, and injection site redness in those up to 1 year of age; fever in children up to age 12, and pain and tenderness in adolescents. In adults the most common side effects are headache, myalgia, and injection site pain and tenderness16

IXIARO® Vaccination Schedule

  • For adults aged 18-65, the vaccine is given in 2 doses, 7 days apart (accelerated schedule) or 28 days apart (standard schedule), and vaccination should be completed 7 days before departure16
  • For pediatric (2 months to <18 years) and older adult (66+ years) travelers, the vaccine is given in 2 doses, 28 days apart (standard schedule), and vaccination should be completed 7 days before departure16
  • A booster dose (third dose)* may be given at least 11 months after completion of the primary immunization series if ongoing exposure or re-exposure to JE virus is expected16

*Children from 14 months to <3 years of age should receive a single 0.25 mL booster dose. Individuals 3 years of age and older should receive a single 0.5 mL booster dose.16

Vaccination & Travel Timeline16

For travelers preparing a trip to Asia

IXIARO® Ease of Administration

IXIARO® is provided as suspension for injection in a single-dose, prefilled syringe.16

• Small-sized packaging for convenient customer storage

• Store in refrigerator at 35° to 46° F (2° to 8° C)16

For more information about
IXIARO® and how to order it visit

For more information about
IXIARO® and how to order it visit

Indication & Usage

IXIARO is a vaccine indicated for the prevention of disease caused by JE virus, approved for use in individuals 2 months of age and older.

Important Safety Information

Severe allergic reaction (e.g., anaphylaxis) after a previous dose of IXIARO, any other Japanese encephalitis vaccine, or any component of IXIARO, including protamine sulfate ─ a compound known to cause hypersensitivity reactions in some individuals ─ is a contraindication to administration of IXIARO.  Individuals with a history of severe allergic reaction to another Japanese encephalitis vaccine may be referred to an allergist for evaluation if immunization with IXIARO might be considered.

Vaccination with IXIARO may not protect all individuals. Immunocompromised individuals may have a diminished immune response to IXIARO.  Syncope can occur in association with administration of injectable vaccines, including IXIARO. Procedures should be in place to prevent injury from falling and manage syncopal reactions.

The most common (>10%) adverse reactions were: fever, irritability, diarrhea, and injection site redness in infants 2 months to <1 year of age; fever in children 1 to <12 years of age; pain and tenderness in adolescents 12 to <18 years of age; and, headache, myalgia, and injection site pain and tenderness in adults.

Healthcare practitioners are encouraged to report negative side effects of vaccines to the US Food and Drug Administration (FDA) and the Centers for Disease Control and Prevention (CDC). Visit www.vaers.hhs.gov or call 1-800-822-7967.  Healthcare practitioners are also encouraged to report inadvertent use in pregnant women to Valneva at 844-349-4276 (8443-IXIARO).

Please see full Prescribing Information.

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Customer Service
+1 866 223 7118

Medical Information
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1807-US-IX-044-1018 | 10/18 | Copyright © 2018 Valneva USA, Inc. All Rights Reserved