Site provided by Valneva USA, Inc.

Progression of JE

About 5 to 15 days after being bitten by an infected mosquito, travelers can develop encephalitis and sudden onset of symptoms, including headache, high fever, disorientation, tremors and convulsions, and coma.4

Select Stage to Learn More

INCUBATION PERIOD7
 

5-15 Days4,7

NON-SPECIFIC SYMPTOMS7
 

• Fever

• Diarrhea

• Headache

• Myalgia

• Nausea and Vomiting

CNS MANIFESTATIONS
 

• Acute encephalopathy

• Change in mental status

• Mild confusion to agitation to coma

• Parkinsonian syndrome

• Upper and lower motor neuron paralysis

• Seizures

Gradual recovery or
Persistence of CNS signs

LONG-TERM IMPAIRMENT

 

• Severe Cognitive and memory impairments

• Psychiatric and behavioral disturbances

• Neuromuscular dysfunction

• Impairment of activities of daily living (ADLs)

• Seizures